The longevity industry is rapidly gaining attention as people become more health-conscious and interested in living longer, healthier lives. In this page, we'll introduce you to some of the most important companies in the longevity industry that are worth following.
These companies are pioneers in the development of cutting-edge technologies, products, and services that can help people live longer, healthier lives.
Altos Labs
A cutting-edge biotech lab that seeks to reverse the aging process.
This company aims to "reprogram" cells to rejuvenate the body. Their main focus is cellular rejuvenation, a cutting-edge technique to reverse age-related cell decline. They've been compared to "biological time travelers" as they work to rewind the cellular clock.
Type: Biotech
Longevity areas: Cellular Senescence and Rejuvenation, Radical life extension
Juvenescence is a life sciences company developing new therapies to increase human healthspan and longevity. Their focus is on developing novel drugs, therapies, and technologies targeting aging and age-related diseases.
Insilico Medicine focuses on AI-driven drug discovery to target aging and age-related diseases. They develop cutting-edge AI technology for predicting molecular targets and generating new drug candidates.
Type: Biotech, AI
Longevity areas: Biohacking, AI-based drug discovery, cellular senescence
Founders: Alex Zhavoronkov, Artur Isaev, Qingsong Zhu
Human Longevity Inc. offers comprehensive genomic and health assessments to detect diseases early and provide personalized treatment plans. Their Health Nucleus platform uses whole-genome sequencing, advanced imaging, and machine learning to detect health risks.
Type: Biotech, Medical
Longevity areas: Biohacking, genomics, precision medicine
Unity Biotechnology focuses on developing drugs to selectively eliminate senescent cells, which contribute to aging and age-related diseases. Their goal is to extend healthspan and improve the quality of life for aging populations. Their lead candidate, UBX1325, targets age-related eye diseases.
Elevian develops regenerative medicines to target aging and age-related diseases. Their focus is on leveraging GDF11, a naturally occurring protein with regenerative properties, to promote tissue repair and regeneration.
Life Biosciences is a research-driven company developing therapies to target the hallmarks of aging. They focus on six pathways of aging and collaborate with academic institutions to advance their research.
Calico Life Sciences is an Alphabet subsidiary responsible for health research and development, life sciences and biotechnology.
Calico is a research and development company focused on understanding the biology of aging and developing interventions to extend healthspan. They partner with external organizations to discover and develop therapies targeting age-related diseases.
BioSplice Therapeutics is focused on discovering and developing RNA-targeted small molecules to treat aging and age-related diseases. Their main product, lorecivivint, is being developed to treat osteoarthritis.
BlueRock Therapeutics is developing cell therapies for degenerative diseases. They focus on using pluripotent stem cells to regenerate damaged tissues in diseases such as Parkinson's and heart failure.
Oisin Biotechnologies is developing gene therapies to remove senescent cells and cancer cells, aiming to extend healthspan and combat age-related diseases.
NaNotics focuses on developing nanoparticles to remove harmful molecules from the body that contribute to aging and age-related diseases. Their "NanoSponges" bind to and neutralize these molecules, promoting health and longevity.
LyGenesis is developing a novel approach to organ regeneration by using lymph nodes as bioreactors to grow functioning ectopic organs. This technology could potentially address organ failure and extend healthspan.
Cell Therapies for life threatening diseases.
Type: Biotech, Medical
Longevity areas: Cell therapies, regenerative medicine, organ regeneration, tissue repair
CohBar focuses on developing mitochondria-based therapeutics to treat aging and age-related diseases. Their research involves the discovery of novel mitochondrial-derived peptides that have the potential to improve healthspan.
Repair Biotechnologies is developing therapies to reverse atherosclerosis and rejuvenate the thymus. Their aim is to target the root causes of age-related diseases and extend healthspan.
Their claim: "The first-in-class Cholesterol Degrading Platform (CDP). Not just a drug or a therapy."
Type: Biotech
Longevity areas: Regenerative medicine, immune system rejuvenation, tissue repair
Celularity is a clinical-stage biotechnology company developing off-the-shelf placental-derived allogeneic cell therapies including genetically modified and unmodified NK cells, engineered T cells including CAR-T cells, and mesenchymal-like adherent stromal cells (ASCs), targeting indications across cancer, immunologic, infectious, and degenerative diseases.
Lineage Cell Therapeutics is developing cell therapies for degenerative diseases using pluripotent stem cells. They focus on conditions such as age-related macular degeneration, spinal cord injury, and cancer.
Their mission is to pioneer a new branch of medicine based on transplanting specific cell types to patients with serious medical conditions.
AgeX Therapeutics focuses on developing novel therapeutics for age-related diseases by targeting the regenerative capabilities of human cells. They are working on products like PureStem and UniverCyte to improve cell function and longevity.
As they claim:
- through PureStem® they have the ability to generate pluripotent stem cell-derived young cells of any type for potential application in a range of degenerative diseases of aging with a high unmet medical need.
- iTR™ is their longevity platform aiming to unlock cellular immortality and regenerative capacity to reverse age-related changes in the body.
Rejuvenate Bio is working on gene therapies to reverse aging in companion animals, with plans to eventually translate their findings to human therapies. They aim to target multiple age-related diseases simultaneously.
Their claim: Unlocking the power of gene expression and epigenetic reprogramming to reverse pre-existing heart disease, metabolic disease, and kidney failure in humans.
Type: Biotech
Longevity areas: Gene therapy, radical life extension, multi-disease targeting
Founders:George Church, Noah Davidsohn, Daniel Oliver
Turn.bio is developing a novel approach called Transient Reprogramming to rejuvenate cells by transiently activating pluripotency genes. This approach could potentially reverse cellular aging and age-related diseases.
As they claim: Turn Biotechnologies develops mRNA medicines that induce the body to heal itself by instructing specific cells to fight disease or repair damaged tissue. We are focused on reprogramming the epigenome – a network of chemical compounds and proteins that control cell functions by influencing which genes are active – to restore capabilities that are often lost with age.
Stealth BioTherapeutics focuses on developing therapies to treat mitochondrial dysfunction in age-related diseases. Their lead product candidate, elamipretide, aims to improve mitochondrial function in patients with various conditions.
Gerostate Alpha aims to discover and develop drugs that target the biology of aging. They use a high-throughput screening platform to identify compounds that can extend lifespan and improve healthspan in animal models.
Type: Biotech
Longevity areas: Drug discovery, biohacking, radical life extension
Founders: Gordon Lithgow, Julie Andersen, Simon Melov
BioAge Labs focuses on developing drugs to treat aging and age-related diseases by targeting the molecular pathways that drive the aging process. They use human data and AI to identify promising drug targets.
Type: Biotech
Longevity areas: AI-based drug discovery, biohacking, age-related diseases
Founders: Kristen Fortney, Eric Verdin, Arvind Gupta
Alkahest is developing plasma-based therapies to treat age-related diseases, with a focus on neurodegenerative and cognitive disorders. They are working on harnessing the regenerative potential of blood factors.
Type: Biotech, Medical
Longevity areas: Regenerative medicine, neurodegeneration, cognitive health
Cleara is a biopharmaceutical R&D company dedicated to discovery and development of therapies against cancer and chronic diseases through selective elimination of subtypes of cellular senescence.
Their mission: Targeting cellular senescence to extend human healthspan at old age and to counteract late stage cancer.
Type: Biotech
Longevity areas: Cellular senescence, senolytic drugs, radical life extension
Elysium Health offers science-based supplements that target the molecular and cellular processes of aging, as well as tests of biological age. Their flagship product, Basis, is designed to boost NAD+ levels, which decline as we age.
Type: Biotech, Nutraceutical
Longevity areas: NAD+ boosting, biohacking, cellular health
Founders: Leonard Guarente, Eric Marcotulli, Dan Alminana
SENS Research Foundation is focused on developing, promoting, and ensuring widespread access to rejuvenation biotechnologies that address the root causes of aging. Their research covers all seven categories of aging damage.
Type: Biotech, Nonprofit
Longevity areas: Regenerative medicine, radical life extension, tissue repair
Apollo Ventures invests in and builds biotech companies focused on aging and age-related diseases. They support innovative projects to develop new therapeutics and diagnostics.
Navitor Pharmaceuticals is developing drugs targeting the mTOR pathway, a key regulator of aging and cellular function. Their approach aims to treat age-related diseases by modulating mTOR signaling.
Deep Longevity uses AI to develop and apply biomarkers of aging for diagnostics, drug discovery, and personalized medicine. Their focus is on identifying molecular signatures that can predict healthspan and lifespan.
Type: Biotech, AI
Longevity areas: AI-based diagnostics, biohacking, personalized medicine
